Dr. Erwin and his team have successfully differentiated stem cells obtain from the intervertebral disc, bone marrow and most recently, articular cartilage, into motor neurons and astrocytes – as well as other cells that are most affected by ALS.

Dr. Erwin and his team have successfully performed transplants in 48 SOD1 mice, using MRIgFUS to open the blood-spinal cord barrier and demonstrated that transplanted stem cells can safely integrate into the spinal cord.

Using this novel stem cell technique, we aim to obtain the stem cell from minimally invasive human nasal cartilage biopsy. The cartilage cells will be reprogrammed in vitro into neural-derived autologous stem cells.  Learn more about Dr. Erwin's autologous adult stem cell research. 

A novel approach using MRI-guided focused ultrasound (MRIgFUS) to open the blood-spinal cord barrier, and non-surgically deliver neural-derived autologous stem cell to the spinal cord of patients with ALS.  Find out more here

Health Canada has already approved the MRIgFUS technique to open the brain-blood barrier in humans, but there is no safety data for the human spinal cord, which has important biological differences when compared to the brain.​

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We advance & accelerate ALS adult stem cell research in Canada.

Help us fund the development of a unique cellular replacement treatment that restores health and motor function for patients with ALS, in order to prevent progression of disease and potentially offer a cure

Adaptive Canuck ALS Foundation ALS Adult Stem Cell Research

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641 Hillcrest Dr, London, Ontario N6K 1A8, Canada
+1.7055213030 • alscanuck@gmail.com

​Dr. Agessandro Abrahão, MD, MSc 

Awarded the Adaptive Canuck ALS Translational Stem Cell Research Fellowship Grant

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Dr. Mark Erwin

This Translational Research Fellowship will accelerate the steps between preclinical stem cell related studies (MRI-guided focused ultrasound technique in animals) and a proof-of-concept, first-in-human study to deliver stem cells to the spinal cord of Canadian patients with ALS. Agessandro’s research plan is detailed here.

Together, we can make a difference


To advance and accelerate the leading ALS adult stem cell science in Canada requires many hands. We've got many successes under our belt, but we need more help, and that's where you come in. 

​While you can volunteer with us directly, even traveling to provide needy families with materials and education, there's much you can do on your own. Contact us to learn more about opportunities and ideas for donating, fundraising, hosting events, campaigning, buying gifts, and involving your school or company.

Dr. Kullervo Hynynen

Learn how you can get involved with Adaptive Canuck ALS Foundation.

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